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Updated: Apr 21, 2026

Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase
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リボヌクレオチド還元酵素における活性サイトチールラジカルによる基板からの水素原子抽出の運動学

Lisa Olshansky1, Arturo A Pizano, Yifeng Wei

  • 1Department of Chemistry and Chemical Biology, Harvard University , 12 Oxford Street, Cambridge, Massachusetts 02138, United States.

Journal of the American Chemical Society
|October 30, 2014
PubMed
まとめ

この研究では,光化学的アプローチを使用してリボヌクレオチド還元酵素 (RNR) 触媒の速度制限ステップを明らかにしています. 光誘発の激素伝播は,3'-C-H結合の分裂を,陽子結合電子移転 (PCET) の最も遅いステップとして明らかにした.

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Radical Formation: Abstraction

The electron of an atom can be abstracted from a compound by a relatively unstable radical to generate a new radical of relatively greater stability. For example, an initiator which forms radicals by homolysis can abstract a suitable species like a hydrogen atom or a halogen atom from a compound to generate a new radical. This ability of radicals to propagate by abstraction is a crucial feature of radical chain reactions.
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