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Updated: May 12, 2026

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
06:01

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Published on: July 6, 2017

再構成された臓器におけるRASおよびMYC腫瘍遺伝子が誘発した多段階がん発生

T C Thompson1, J Southgate, G Kitchener

  • 1Imperial Cancer Research Fund, London, England.

Cell
|March 24, 1989
PubMed
まとめ

マウスの前立腺細胞で単一の腫瘍遺伝子 (RASまたはMYC) を活性化すると,明確な前立腺病変が生じます. 連続した腫瘍遺伝子の活性化と遺伝子増幅は,腫瘍の進行とがんの発症を促します.

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