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関連する概念動画

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

4.8K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
4.8K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.6K
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

1.2K
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
1.2K
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

3.5K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
3.5K
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

651
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
651
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

1.7K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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関連する実験動画

Updated: Apr 21, 2026

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
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発射分子が保存された心不全における右心室機能:コミュニティベースの研究.

Selma F Mohammed1, Imad Hussain2, Omar F AbouEzzeddine

  • 1From the Division of Cardiovascular Diseases (S.F.M., I.H., O.F.A.E., H.T., S.H.K., V.L.R., M.M.R.), Mayo Graduate School (S.F.M.), and Department of Health Sciences Research (V.L.R.), Mayo Clinic, Rochester, MN; and Division of Cardiovascular Medicine, Temple University, Philadelphia, PA (P.F.). mohammed.selma@mayo.edu.

Circulation
|November 14, 2014
PubMed
まとめ

右心室シストリック機能不全 (RVD) は,保存されたエジェクション分数 (HFpEF) 患者の心不全において一般的であり,より高い死亡率と入院率を含む,より悪い結果を予測します. この発見は,HFpEF管理におけるRVDの臨床的重要性を強調しています.

キーワード:
ディアストロリー (diastole) とは心不全は,心不全を意味する.高血圧,肺動脈高血圧などです.右心室機能障害,右心室機能障害など

さらに関連する動画

Comprehensive Echocardiographic Assessment of Right Ventricle Function in a Rat Model of Pulmonary Arterial Hypertension
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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関連する実験動画

Last Updated: Apr 21, 2026

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Comprehensive Echocardiographic Assessment of Right Ventricle Function in a Rat Model of Pulmonary Arterial Hypertension
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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科学分野:

  • 心臓病学 心臓病学
  • エコーカルディオグラフィー エコーカルディオグラフィー
  • 心不全に関する研究

背景:

  • 右心室シストリック機能不全 (RVD) の罹患率と保存されたエジェクション分数 (HFpEF) による心不全における有意性は不明である.
  • HFpEFは重要な患者集団に影響を与え,貢献する要因と予後指標をよりよく理解する必要がある.

研究 の 目的:

  • コミュニティベースのHFpEFコホートにおけるRVDの有病率と臨床的重要性を特徴付ける.
  • RVDと臨床的特徴,エコーカルディオグラフィの発見,患者のアウトカムとの関連を決定する.

主な方法:

  • フレミングハム基準を満たした562人のHFpEF患者 (エジェクション分数 ≥50%) の見込みの特定.
  • 診断とフォローアップのエコーカルディオグラフィは,三環状平面シストリックエクスクルションと半量的な2D評価を使用してRV機能を評価します.
  • 特定原因による死亡率とHF入院率の分析,関連する共変数で調整.

主要な成果:

  • RVDは,HFpEF患者のかなりの割合で特定され,しばしば心房細動,ペースメーカー,および利尿薬の使用と関連していました.
  • RVDの患者は,左下心室のエジェクション分数,より悪い透析機能不全,低血圧,より高い肺動脈静脈圧,より重度のRV拡大と三体吐を示した.
  • RVDは,使用された定義 (半量的なまたは三角形環状平面シストリックエクスクルシオン) にかかわらず,独立してより高い全因および心血管死亡率,およびHF入院率の増加を予測しました.

結論:

  • 右心室シストリック機能不全は,コミュニティベースのHFpEF患者で頻繁に発見されます.
  • RVDは,より高度なHF特性に関連しており,より悪い予後を予告します.
  • RV機能の評価は,HFpEFのリスク分層化と管理に不可欠です.