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Updated: Apr 20, 2026

Surface Passivation for Single-molecule Protein Studies
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Published on: April 24, 2014

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より高い熱力学およびタンパク質分解の安定性のためのタンパク質のPEGylationサイトを選択する基準

Paul B Lawrence1, Yulian Gavrilov, Sam S Matthews

  • 1Department of Chemistry and Biochemistry, Brigham Young University , Provo, Utah 84602, United States.

Journal of the American Chemical Society
|November 20, 2014
PubMed
まとめ

サイト固有のPEGylationは,形状の安定性を高めることで,タンパク質の薬物特性を強化します. この研究は,最適なPEGylationサイトのための予測方法を開発し,薬の有効性と安定性を改善します.

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