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Updated: Apr 20, 2026

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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ストカスティックゲートダイナミクスは,ユビキチン化酵素の触媒活性を調節する

Manoj K Rout1, Curtis D Hodge, Craig J Markin

  • 1Department of Biochemistry, University of Alberta , Edmonton, Alberta T6G 2H7, Canada.

Journal of the American Chemical Society
|November 26, 2014
PubMed
まとめ

Ubc13酵素の柔軟なループダイナミクスは,DNA損傷と免疫反応に不可欠な触媒活動を制御する. このストカスティックゲートメカニズムは,細胞シグナル伝達に不可欠なLys 63結合ポリユビキチン鎖合成を調節する.

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