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Updated: Apr 20, 2026

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction
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Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction

Published on: July 7, 2023

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PD-1阻害は,適応性免疫抵抗を抑制することによって反応を誘導する

Paul C Tumeh1, Christina L Harview2, Jennifer H Yearley3

  • 11] University of California Los Angeles (UCLA), Los Angeles, California 90095, USA [2] Jonsson Comprehensive Cancer Center, Los Angeles, California 90095, USA.

Nature
|November 28, 2014
PubMed
まとめ

腫瘍の縁にある,PD-1/PD-L1を発現する既にあるCD8 (((+) T細胞は,抗PD-1がん治療に対する反応を予測する. この免疫抵抗メカニズムは,腫瘍の回帰のためにこれらのT細胞の必要性を強調しています.

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