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Updated: Apr 20, 2026

Identification Of Erythromyeloid Progenitors And Their Progeny In The Mouse Embryo By Flow Cytometry
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組織に定着するマクロファージは,黄膜から派生したエリトロミエロイドの祖先から発生します

Elisa Gomez Perdiguero1, Kay Klapproth2, Christian Schulz1

  • 1Centre for Molecular and Cellular Biology of Inflammation (CMCBI), King's College London, London SE1 1UL, UK.

Nature
|December 4, 2014
PubMed
まとめ

大人の組織に居住するマクロファージのほとんどは,成人の造血性幹細胞 (HSC) ではなく,卵黄袋の赤血球性ミエロイド原始細胞 (EMP) から発生します. これらのEMPは,開発初期にクッファー細胞やマイクログリアのような主要なマクロファージ集団を確立します.

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