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Updated: Apr 20, 2026

Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis
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ESCRT機械は,ヘッジホッグの分泌と長距離活動を調節しています

Tamás Matusek1, Franz Wendler1, Sophie Polès1

  • 11] Université de Nice Sophia Antipolis, iBV, UMR 7277, 06100 Nice, France [2] CNRS, iBV, UMR 7277, 06100 Nice, France [3] INSERM, iBV, U1091, 06100 Nice, France.

Nature
|December 5, 2014
PubMed
まとめ

輸送に必要な内分体分類複合体 (ESCRT) は,ヘッジホッグ (Hh) タンパク質の分泌とドロソフィラの発達における長距離シグナル伝達に不可欠である. ESCRTは,組織パターニングとターゲット誘導に不可欠な細胞外膀経由でHh輸送を促進します.

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