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ベータ・ラクタム抗生物質は,細菌の細胞壁合成装置の致命的な機能障害を誘発する

Hongbaek Cho1, Tsuyoshi Uehara1, Thomas G Bernhardt1

  • 1Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|December 7, 2014
PubMed
まとめ

ベータ・ラクタム抗生物質は,ペニシリンと同様に,細菌の細胞壁の合成と分解の無駄なサイクルを誘発します. このプロセスは細胞資源を枯渇させ,抗生物質の有効性を高め,薬の開発のための新しい標的を明らかにします.

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