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Updated: Apr 19, 2026

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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ステニルアミンプロトコル (SnAP) 反応剤とケトンによる飽和型スパイロサイクルのN-ヘテロサイクルの1段階合成

Woon-Yew Siau1, Jeffrey W Bode

  • 1Laboratorium für Organische Chemie, Department of Chemistry and Applied Biosciences, ETH-Zürich , 8093 Zürich, Switzerland.

Journal of the American Chemical Society
|December 9, 2014
PubMed
まとめ

新しい方法では,サイクルケトンとスタンニルアミンプロトコル (SnAP) 反応剤を組み合わせて,貴重なスパイロサイクルアミン・スキャフォールドを作成します. この効率的な合成は,薬剤の発見と開発のための新しい道を開く.

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