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Updated: Apr 19, 2026

In vitro Cell Migration and Invasion Assays
09:55

In vitro Cell Migration and Invasion Assays

Published on: June 1, 2014

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化学的に交互に結合したノッティン・ダイマーが,ピコモラー親和性を持つインテグリンと結合し,腫瘍細胞の移転と増殖を抑制する

Jun W Kim1, Frank V Cochran, Jennifer R Cochran

  • 1Departments of †Bioengineering and ‡Chemical Engineering, Stanford University , Stanford, California 94305, United States.

Journal of the American Chemical Society
|December 9, 2014
PubMed
まとめ

研究者らは,オキシム化学を用いた新しい二重インテグリン阻害剤を開発し,腫瘍細胞への結合親和性が著しく向上した. このアプローチは,血管新生と転移を標的としたより効果的ながん治療法の開発に希望を示しています.

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