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Updated: Apr 19, 2026

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers
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In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers

Published on: August 1, 2014

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健康な個体において,アナーギック現象型を持つ自己反応性CD8+T細胞の検出

Yuka Maeda1, Hiroyoshi Nishikawa2, Daisuke Sugiyama1

  • 1Experimental Immunology, Immunology Frontier Research Center (IFReC-WPI), Osaka University, Osaka 565-0871, Japan.

Science (New York, N.Y.)
|December 20, 2014
PubMed
まとめ

調節性T (Treg) 細胞は,自己反応性CD8 (((+)) T細胞でアナーギーを誘導し,自己免疫を予防する. 健康な個体で特定された無能なT細胞は,このメカニズムが免疫的耐性を維持することを示唆しています.

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