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アポプトティックカスパスは,ミトコンドリアDNAによるタイプIインターフェロンの誘導を防ぐ

Anthony Rongvaux1, Ruaidhrí Jackson1, Christian C D Harman1

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Cell
|December 20, 2014
PubMed
まとめ

ミトコンドリアは細胞死免疫を制御する. 有効なカスパスがなければ,ミトコンドリア損傷は抗ウイルス防御のためのタイプIインターフェロン (IFN) を誘発するが,カスパスはこの応答を無効化する.

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