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Updated: Jul 20, 2026

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
07:18

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing

Published on: January 22, 2019

HIV-1 Tatタンパク質は,転写の開始を増加させ,延長を安定させます

M F Laspia1, A P Rice, M B Mathews

  • 1Cold Spring Harbor Laboratory, New York 11724.

Cell
|October 20, 1989
PubMed
まとめ

ヒト免疫不全ウイルス-1 (HIV-1) のタットタンパク質は,ウイルスRNAの全長生成を特異的に強化し,転写停止を抑制します. アデノウイルスE1Aタンパク質は,ウイルスのRNA合成を大きく増加させるが,一時停止に影響を与えない.

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