関連する実験動画

Updated: Apr 19, 2026

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
05:51

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method

Published on: July 19, 2019

6.8K

最も反応性の高いアミドは,シス・トランス・インターコンバージョンの移行状態を模倣する

Igor V Komarov1, Stanislav Yanik, Aleksandr Yu Ishchenko

  • 1Institute of High Technologies and ‡Chemistry Department, Taras Shevchenko National University of Kyiv , Volodymyrska 60 and 64, 01601 Kyiv, Ukraine.

Journal of the American Chemical Society
|December 24, 2014
PubMed
まとめ

研究者らは90度回転したユニークなアミド,1-アザトリサイクロ[3.1.1.1(3,7) ]デカン-2-オンを合成した. この高度に反応性の高い化合物は,生物系におけるアミド結合回転の移行状態模倣として機能する.

さらに関連する動画

Interactive Molecular Model Assembly with 3D Printing06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

11.3K
High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal06:24

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

Published on: October 31, 2019

7.0K

関連する概念動画

Disubstituted Cyclohexanes: cis-trans Isomerism02:37

Disubstituted Cyclohexanes: cis-trans Isomerism

Depending upon the different spatial orientation of the substituents, the disubstituted cycloalkanes exhibit two types of stereoisomers. The cis isomers have the substituents on the same side of the ring, whereas the trans isomers have the substituents on the opposite sides. These stereoisomers exhibit different physical properties and cannot be interconverted without breaking the carbon-carbon bonds.
In cyclohexane, the substituents can occupy different positions generating distinct isomers....
15.3K
[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement01:21

[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement

The Cope rearrangement is classified as a [3,3] sigmatropic shift in 1,5-dienes, leading to a more stable, isomeric 1,5-diene. The reaction involves a concerted movement of six electrons, four from two π bonds and two from a σ bond, via an energetically favorable chair-like transition state.
3.7K
Stereoisomerism of Cyclic Compounds02:33

Stereoisomerism of Cyclic Compounds

In this lesson, we delve into the role of ring conformation and its stability, which determines the spatial arrangement and, consequently, the molecular symmetry and stereoisomerism of cyclic compounds. 1,2-Dimethylcyclohexane is used as a case study to evaluate the possible number of stereoisomers. Here, given the multiple (n = 2) chiral centers, there are 2n = 4 possible configurations that lack a plane of symmetry, as the ring skeleton exists in a non-planar chair conformation. In addition,...
12.0K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

2.8K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

3.3K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
9.5K