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Updated: Apr 19, 2026

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胎盤アデノシンシグナル伝達の上昇は,子宮内閉塞前症候群の病原化に寄与する

Takayuki Iriyama1, Kaiqi Sun1, Nicholas F Parchim1

  • 1From Departments of Biochemistry and Molecular Biology (T.I., K.S., N.F.P., J.L., C.Z., A.S., M.R.B., R.E.K., Y.X.) and Department of Obstetrics, Gynecology, and Reproductive Sciences (L.A.H., S.C.B., B.M.S.), University of Texas Medical School at Houston: Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Japan (T.I.); Graduate School of Biomedical Sciences, University of Texas, Houston (K.S., N.F.P., M.R.B, R.E.K., Y.X.); Department of Urology (C.Z.), Xiangya Hospital of Central South University, Changsha, Hunan, China; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, (L-N. L.C., T.-S.C.); and Department of Pathology, Texas Children's Hospital, Houston (M.J.H.).

Circulation
|December 25, 2014
PubMed
まとめ

CD73によって誘発される慢性的に上昇した胎盤アデノシンは,出産前の特性を引き起こします. 過剰なA2Bアデノシン受容体 (ADORA2B) 信号は,この高血圧妊娠障害を悪化させ,新たな治療標的を明らかにします.

キーワード:
アデノシン (Adenosine) とは高血圧,高血圧を患っている.モデル,動物モデル,動物モデル産前不妊症 産前不妊症 産前不妊症妊娠中 妊娠中 妊娠中

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