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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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サイクル化カスケードは,N-アミジルラジカルを通って,高度に機能的な異環構造のスキャフォールドに向かって進みます

Noelia Fuentes1, Wangqing Kong, Luis Fernández-Sánchez

  • 1Department of Chemistry, University of Zürich , Winterthurerstrasse 190, 8057 Zürich, Switzerland.

Journal of the American Chemical Society
|January 7, 2015
PubMed
まとめ

この研究は,複雑なヘテロサイクルを合成するためにN- ((アリルシルフォニル) アクリラミドを使用した新しい急激カスケード反応を紹介しています. これらの方法は,効率的に複数の結合を形成し,迅速な分子複合性の構築を可能にします.

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