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Updated: Apr 18, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

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スナップショット:ファンコーニ貧血と関連するタンパク質

Anderson T Wang1, Agata Smogorzewska1

  • 1Laboratory of Genome Maintenance, The Rockefeller University, New York, NY 10065, USA.

Cell
|January 17, 2015
PubMed
まとめ

ファンコニ貧血 (Fanconi anemia) は,FANC遺伝子の変異によって引き起こされる珍しい遺伝疾患で,DNA修復の欠陥と癌のリスクの増加につながる. この要約は,ファンコーニ貧血-BRCA経路の重要な要因を説明しています.

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Experimental Approaches for Biochemical Analysis of Glial Fibrillary Acidic Protein and Its Disease-associated Variants

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Cytoskeletal Accessory Proteins01:13

Cytoskeletal Accessory Proteins

The cytoskeleton is an essential cell component that plays several structural and functional roles. However, the filaments that make up the cytoskeleton cannot function independently and depend on the accessory or ancillary proteins to effectively carry out their function. Accessory proteins associate with cytoskeletal filaments and their monomers, aiding filament formation and function. They also help in the cross-communication among cytoskeletal filaments. Cytoskeletal accessory proteins are...
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Actin Polymerization and Cell Motility01:13

Actin Polymerization and Cell Motility

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Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate....
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Protein Complexes with Interchangeable Parts

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Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
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The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and II are acidic and basic keratin proteins. Type III is of mesodermal origin and comprises four proteins: vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Vimentin is commonly found in mesenchymal cells, desmin in muscle cells, GFAP in astrocytes, while peripherin is found in peripheral nervous system neurons (PNS). Type...
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Glucose Transporters

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