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Updated: Apr 18, 2026

Hypothalamic Kisspeptin Neurons as a Target for Whole-Cell Patch-Clamp Recordings
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Published on: March 17, 2023

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ヒポタラムニューロンにおけるMC4RとKir7.1のGタンパク質独立結合

Masoud Ghamari-Langroudi1, Gregory J Digby1, Julien A Sebag1

  • 1Department of Molecular Physiology &Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.

Nature
|January 21, 2015
PubMed
まとめ

視床下部のメラノコルチン-4受容体 (MC4R) 信号伝達は,エネルギーバランスを調節する. 新しい研究は,α-MSHとAgRPが,従来のGαs経路とは独立して,カリウムチャネルKir7.1経由でニューロン活動を調節することを明らかにしています.

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