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Fluorescence Anisotropy as a Tool to Study Protein-protein Interactions
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球状結合阻害剤のステリックシールドと多値性の効果のサイズ依存性

Jonathan Vonnemann1, Susanne Liese, Christian Kuehne

  • 1Institute of Chemistry and Biochemistry, †Institute of Theoretical Physics, and §Research Centre of Electron Microscopy and Core Facility BioSupraMol, Institute of Chemistry and Biochemistry, Freie Universität Berlin , Berlin, Germany.

Journal of the American Chemical Society
|January 28, 2015
PubMed
まとめ

多価ナノ粒子阻害剤は,ウイルス感染症の予防に有望であることが示されています. 彼らの効率は主に多値性効果に依存し,ステリックシールドはマイナーな役割を果たし,最適な阻害剤設計を導く.

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