イソチアゾリノーン防腐剤:コスメティック性皮膚炎の流行が続いている原因
1Department of Dermatology, Carolus & Willem-Alexander Hospital, MD's-Hertogenbosch, Netherlands.
Lancet (London, England)
|February 11, 1989
まとめ
メチルイソチアゾリノーンとメチルクロイソチアゾリノンは,特に留置製品における,化粧品アレルギーの一般的な原因です. これ以上のアレルギー反応を防ぐために,化粧品での使用を停止する必要があります.
科学分野:
- 皮膚科 皮膚科について
- 化粧品科学 コスメティック科学
- 毒理学 毒理学 毒理学
背景:
- メチルイソチアゾリノンとメチルクロロイソチアゾリノン (MI/MCI) の混合物は,化粧品やトイレットペーパーで広く使用されている防腐剤です.
- この保存剤系は,ヨーロッパ諸国におけるアレルギー性コンタクト皮膚炎の重要な原因として特定されています.
研究 の 目的:
- 化粧品アレルギーの流行にMI/MCIの役割を強調する.
- 留置された化粧品におけるMI/MCIの使用を中止することを勧告する.
- より厳格な毒性学的評価と,化粧品の化学物質の必須成分ラベルを提唱する.
主な方法:
- MI/MCIに関連した化粧品アレルギーの報告された症例のレビュー.
- 敏感化に関連した製品タイプの分析.
- アレルギー性コンタクト皮膚炎の流行病学的傾向の評価.
主要な成果:
- MI/MCIによって引き起こされる化粧品アレルギーの主要な原因は,保湿クリームなどの残った化粧品です.
- この防腐剤の広範な使用に関連して,アレルギー性コンタクト皮膚炎の有意な増加が観察されています.
- 現在の規制の審査は,そのような広範な感受性を防ぐには不十分かもしれません.
結論:
- 化粧品およびトイレットペーパー製品,特に留置型製品におけるMI/MCI保存剤システムの使用は,放棄されるべきである.
- 新しい化粧品の成分に対する毒性学的評価の強化は,市場に導入する前に決定的に重要です.
- 必須の成分表示は,消費者の安全と化粧品に関する情報に基づいた選択のために不可欠です.
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