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Updated: Apr 17, 2026

A Protocol for Analyzing Hepatitis C Virus Replication
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ウイルスの複製. C型肝炎ウイルスのポリメラーゼによるRNA複製の構造的基礎

Todd C Appleby1, Jason K Perry2, Eisuke Murakami2

  • 1Gilead Sciences, 333 Lakeside Drive, Foster City, CA 94404, USA. todd.appleby@gilead.com tedwards@be4.com.

Science (New York, N.Y.)
|February 14, 2015
PubMed
まとめ

肝炎Cウイルス (HCV) のRNA複製メカニズムは,NS5Bポリメラーゼの結晶構造を用いて詳細に研究されました. これらの構造を理解することは,HCV治療のための新しい核酸ナログ阻害剤の開発に役立ちます.

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