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Updated: Apr 17, 2026

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
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Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

Published on: December 21, 2019

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セル外環境を形作るサーピンで,インフルエンザAウイルスの成熟を防ぐ

Meike Dittmann1, Hans-Heinrich Hoffmann1, Margaret A Scull1

  • 1Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

Cell
|February 14, 2015
PubMed
まとめ

インターフェロン刺激遺伝子 (ISG) は,抗ウイルス防御機能を提供する. この研究では,SERPINE1 (PAI-1) がインフルエンザAウイルス (IAV) を標的とした細胞外プロテアゼを標的とし,ウイルスの感染性を低下させ,それを阻害するISGとして特定されました.

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