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Updated: Dec 11, 2025

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CpGの構造的基礎と,トール型受容体9による抑制性DNA認識

Umeharu Ohto1, Takuma Shibata2, Hiromi Tanji1

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Nature
|February 18, 2015
PubMed
まとめ

トール型受容体9 (TLR9) の構造に関する洞察は,それが細菌のDNAに結合し,先天的免疫を誘発する方法を示しています. これらの相互作用を理解することは,新しい免疫療法を開発するための鍵です.

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