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Updated: Apr 17, 2026

Assessment of Open Probability of the Mitochondrial Permeability Transition Pore in the Setting of Coenzyme Q Excess
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モリブデンコファクター生物合成におけるGTP 3',8-サイクラゼによるC-ターミナルグリシンゲートラジカルイニシアチブ

Bradley M Hover1, Kenichi Yokoyama

  • 1Department of Biochemistry, Duke University Medical Center , Durham, North Carolina 27710, United States.

Journal of the American Chemical Society
|February 21, 2015
PubMed
まとめ

MOCS1A酵素のGGモチーフは,モリブデン共因子生物合成に不可欠である. このモチーフの変異は酵素機能を破壊し,致命的な代謝障害であるモコ欠乏症 (MoCD) に繋がります.

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