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Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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α-アミノ酸のリガンド活性化β-C-Hアリレーションは,シンプルで実用的な補助的補助剤を用いて行われます

Gang Chen1, Toshihiko Shigenari, Pankaj Jain

  • 1Department of Chemistry, The Scripps Research Institute , 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|February 21, 2015
PubMed
まとめ

研究者は,カルボキシル酸のパラジウム触媒 β-C-H アリレーションを改善するために,新しいピリジン型リガンドを開発しました. この方法は,非自然なアミノ酸や生物活性分子などの貴重な化合物の合成を強化します.

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