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Updated: Apr 17, 2026

Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics DCAF
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免疫抑制性抗体と薬物の結合体である

Rongsheng E Wang1, Tao Liu, Ying Wang

  • 1Department of Chemistry and the Skaggs Institute for Chemical Biology and ‡Department of Immunology and Microbial Science, The Scripps Research Institute , La Jolla, California 92037, United States.

Journal of the American Chemical Society
|February 21, 2015
PubMed
まとめ

新しい抗体-薬物結合体 (ADC) は,ダサチニブで選択的にTリンパ球を標的とし,T細胞活性化を抑制します. この新しいアプローチは,強化された安全性プロファイルを持つ潜在的に新しい免疫抑制薬のクラスを提供します.

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