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Updated: Apr 17, 2026

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二次性ADP-リボースとその構造をヒトのポリ (ADP-リボース) グライコヒドロラゼと合成する

Michael J Lambrecht1, Matthew Brichacek1, Eva Barkauskaite2

  • 1†Department of Chemistry, Roger Adams Laboratory, University of Illinois, 600 South Mathews, Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|February 24, 2015
PubMed
まとめ

化学的に合成されたADP-リボース二分子は,構造研究のために均質なポリ ((ADP-リボース) (PAR) を提供します. この画期的な発見により,ヒトのPARGの最初のコクリスタル構造が実現し,細胞プロセスにおけるPAR-タンパク質の相互作用に関する理解が進んでいます.

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