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Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF
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低体質POMCニューロンは,カンナビノイド誘発の栄養を促進する

Marco Koch1, Luis Varela2, Jae Geun Kim2

  • 11] Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA [2] Institute of Anatomy, University of Leipzig, 04103 Leipzig, Germany.

Nature
|February 25, 2015
PubMed
まとめ

カンナビノイド受容体1 (CB1R) の活性化は,驚くほど,下体内のプロオピオメラノコルチン (POMC) ニューロン活動を増加させ,栄養を促します. カナビノイド駆動の栄養におけるこの予期せぬPOMCニューロン役割は,β-エンドルフィン放出とミトコンドリアの適応を含む.

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