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Updated: Apr 17, 2026

Engineering and Evolution of Synthetic Adeno-Associated Virus AAV Gene Therapy Vectors via DNA Family Shuffling
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Published on: April 2, 2012

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AAVで発現するeCD4-Igは,複数のSHIVの挑戦から永続的な保護を提供します.

Matthew R Gardner1, Lisa M Kattenhorn2, Hema R Kondur1

  • 1Department of Infectious Diseases, The Scripps Research Institute, Jupiter, Florida 33458, USA.

Nature
|February 25, 2015
PubMed
まとめ

強力なHIV-1侵入阻害剤であるeCD4-Igを供給するアデノ関連ウイルス (AAV) ベクトルは,潜在的なワクチン代替を提供している. このアプローチは,マカカが類人猿ヒト免疫不全ウイルスに抵抗することを証明した.

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