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Updated: Apr 16, 2026

Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies
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マルブルクウイルスのヒト抗体媒介による中和のメカニズム

Andrew I Flyak1, Philipp A Ilinykh2, Charles D Murin3

  • 1Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA.

Cell
|February 28, 2015
PubMed
まとめ

研究者らは,マーブルクウイルス (MARV) の生存者からの中和抗体を特定し,MARVグリコプロテインを標的とした. これらの抗体は,暴露された受容体結合部位に結合することで,MARVを抑制し,フィロウイルス抑制のための新しいメカニズムを提供します.

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