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Updated: Jul 6, 2026

Induction and Analysis of Epithelial to Mesenchymal Transition
10:37

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Published on: August 27, 2013

循環型AMPは,CREBをセルリン133でリン酸化することによって,ソマトスタチン遺伝子転写を刺激する

G A Gonzalez1, M R Montminy

  • 1Clayton Foundation Laboratory for Peptide Biology, Salk Institute, La Jolla, California 92037.

Cell
|November 17, 1989
PubMed
まとめ

セル-133でのCREBのリン酸化は,cAMP反応性遺伝子転写に不可欠である. この研究では,フォルスコリンは生体内でCREBのリン酸化を誘導し,遺伝子発現を活性化することを示しています.

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