エドキサバン投与量,濃度,抗ファクターXA活性,およびアウトカムとの関連:ランダム化され,ダブルブラインドで実施されたENGAGE AF-TIMI 48試験のデータの分析

Christian T Ruff1, Robert P Giugliano1, Eugene Braunwald1

  • 1Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

PubMed
まとめ

エドキサバンの投与量を減らし,心房細動の患者に投与することで,過剰な薬剤濃度と出血リスクが防止されました. 臨床的要因に基づいてエドキサバンの投与量を調整することで,脳卒中予防のための患者のアウトカムを最適化します.

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