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Updated: Aug 2, 2026

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
09:53

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

Published on: February 6, 2017

モノクローナル抗体によって認識される細胞毒性Tリンパ球T200グリコプロテインの機能的修正

L Lefrançois, M J Bevan

    Nature
    |April 4, 1985
    PubMed
    まとめ

    細胞毒性Tリンパ球 (CTLs) は,標的細胞を破壊するために,表面上の特定のT200タンパク質の改変を利用します. これらの変異は,活性化されたT細胞に限定され,CTL機能にとって極めて重要であり,抗体によって阻害され得る.

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