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Updated: Apr 15, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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プロミスキュアス・ランチペプチド・シンセテーゼProcMによる製品形成は,運動制御下にある

Yi Yu1, Subha Mukherjee1, Wilfred A van der Donk1

  • 1†Department of Biochemistry, ‡Department of Chemistry, and §Howard Hughes Medical Institute, University of Illinois at Urbana-Champaign, 600 S. Mathews Ave. Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|March 25, 2015
PubMed
まとめ

ランチペプチド合成酵素ProcMは高い製品選択性を示しており,その変異はサイクル化率と地域選択性に影響する. 初期環形成は,熱力学的制御ではなく,最終製品のトポロジーを決定する.

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