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Updated: Apr 15, 2026

Proteomics to Identify Proteins Interacting with P2X2 Ligand-Gated Cation Channels
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人間のP2Y1受容体の2つの異なったリガンド結合部位

Dandan Zhang1, Zhan-Guo Gao2, Kaihua Zhang1

  • 1CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.

Nature
|March 31, 2015
PubMed
まとめ

研究者らは,P2Y1受容体 (P2Y1R) が2つのアンタゴニストと結合する結晶構造を決定した. これらの構造は,血小板の集積を標的とする新しい抗血栓薬の開発に不可欠な,明確な結合部位を明らかにします.

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