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Updated: Apr 15, 2026

RNAi Interference by dsRNA Injection into Drosophila Embryos
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ドロソフィラRNAi酵素複合体の組み立てにおける基本的なステップを定義する

Shintaro Iwasaki1, Hiroshi M Sasaki1, Yuriko Sakaguchi2

  • 1Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan.

Nature
|March 31, 2015
PubMed
まとめ

チャペロンタンパク質は,siRNA複合体とArgonaute 2 (Ago2) の間の相互作用を安定させ,RNA誘発サイレンシング複合体 (RISC) の組み立てを促進します. このプロセスは,小さな干渉RNAs (siRNAs) によって媒介される遺伝子サイレンシングに不可欠です.

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