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構造生物学 構造生物学について CRISPR-Cmr複合体の構造は,RNAの標的の位置づけの方法を明らかにしています

David W Taylor1, Yifan Zhu2, Raymond H J Staals2

  • 1Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA. California Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|April 4, 2015
PubMed
まとめ

バクテリアは,適応免疫のためにCRISPR-Casシステムを使用します. タイプIIIのCRISPR-Cas複合体は,Cmrのように,螺旋状のタンパク質の配置を使用して単一鎖RNAを標的とし,特定の間隔でそれを割ります.

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