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Updated: Apr 14, 2026

Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons
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細胞毒性腫れの原因であるニューロン腫れの細胞メカニズム

Ravi L Rungta1, Hyun B Choi1, John R Tyson2

  • 1Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 2B5, Canada.

Cell
|April 25, 2015
PubMed
まとめ

激しいナトリウム流入は,SLC26A11経由でクロライドの侵入を誘発し,神経細胞の腫れを引き起こし,脳腫れで死亡します. このイオンチャネルを遮断すると,細胞死が減り,潜在的な治療標的となる.

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