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HLA-DRB1ハプロタイプとリウマチ性関節炎の関連性,重症度,死亡率,治療への反応

Sebastien Viatte1, Darren Plant2, Buhm Han3

  • 1Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, England.

JAMA
|April 29, 2015
PubMed
まとめ

特定のHLA-DRB1ハプロタイプは,リウマチ性関節炎 (RA) の進行に影響を与え,放射線学的損傷と死亡率を増加させ,腫瘍死滅因子 (TNF) 阻害剤に対する反応を改善します.

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