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Updated: Apr 13, 2026

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
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アロゲン性IgGとデンドリット細胞刺激を組み合わせると,抗腫瘍T細胞免疫を誘発する

Yaron Carmi1, Matthew H Spitzer2, Ian L Linde1

  • 1School of Medicine, Department of Pathology, Stanford University, Palo Alto, California 94305, USA.

Nature
|April 30, 2015
PubMed
まとめ

自然に発生するIgG抗体は,アロゲン性腫瘍に結合し, dendritic cells (DCs) を介してT細胞を活性化することによって拒絶を開始します. この発見により,マウスの様々ながんの治療に成功し,ヒトのがんの免疫療法にも期待を寄せている.

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