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Updated: Aug 10, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
11:12

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

発芽中心における抗原駆動的選択のメカニズム

Y J Liu1, D E Joshua, G T Williams

  • 1Department of Immunology, University of Birmingham Medical School, UK.

Nature
|December 21, 1989
PubMed
まとめ

中心細胞と呼ばれるB細胞は,抗原受容体やCD40.0経由で活性化されない限り,アポプトーシスを受けます. このプログラムされた細胞死は,免疫反応の際に高親和性抗体の選択に不可欠です.

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