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クロピドグレルとアスピリンの併用で,急性軽度の脳卒中または一時的な性血病発作 (CHANCE) 試験: 1 年間の結果

Yilong Wang1, Yuesong Pan1, Xingquan Zhao1

  • 1From Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Yilong Wang, Y.P., X.Z., H.L., LL., X.M., A.W., C.W., Yongjun Wang); China National Clinical Research Center for Neurological Diseases, Beijing, China (Yilong Wang, Y.P., X.Z., H.L., LL., X.M., A.W., C.W., Yongjun Wang); Center of Stroke, Beijing Institute for Brain Disorders, China (Yilong Wang, Y.P., X.Z., H.L., LL., X.M., A.W., C.W., Yongjun Wang); Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, China (Yilong Wang, Y.P., X.Z., H.L., LL., X.M., A.W., C.W., Yongjun Wang); INI Stroke Network, OSF Healthcare System, University of Illinois College of Medicine, Peoria (D.W.); and Dell Medical School, University of Texas at Austin (S.C.J.).

Circulation
|May 10, 2015
PubMed
まとめ

急性非障害性脳血管疾患 (CHANCE) の高リスク患者におけるクロピドグレル試験は,クロピドグレルとアスピリンの併用が1年間にわたって脳卒中のリスクを大幅に低下させることを実証しました. この二重抗血小板治療は安全であることが証明され,アスピリン単独と比較して出血の増加はなかった.

キーワード:
クロピドグレロゲルは,発血不全発作,一時的な発作,一時的な発作患者のアウトカムアセスメント評価ストローク ストローク ストローク ストローク ストローク

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