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Updated: Apr 12, 2026

Assessment of Cellular Bioenergetics in Mouse Hematopoietic Stem and Primitive Progenitor Cells using the Extracellular Flux Analyzer
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Assessment of Cellular Bioenergetics in Mouse Hematopoietic Stem and Primitive Progenitor Cells using the Extracellular Flux Analyzer

Published on: September 24, 2021

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ミトコンドリアのClpXは,ヘム生物合成とエリトポエーゼスの重要な酵素を活性化させます

Julia R Kardon1, Yvette Y Yien2, Nicholas C Huston2

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cell
|May 11, 2015
PubMed
まとめ

ミトコンドリアのClpX (mtClpX) はヘム生物合成に不可欠であり,ALA合成酵素の活性を直接刺激する. このAAA+展開酵素は,酵母と脊椎動物におけるヘム産生に不可欠であり,エリトロポエシスに影響を与えます.

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