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Updated: Apr 12, 2026

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation
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PPAR-αとグルココルチコイド受容体は,赤色素原体の自己再生を促進するために連携します

Hsiang-Ying Lee1, Xiaofei Gao1, M Inmaculada Barrasa1

  • 1Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|May 14, 2015
PubMed
まとめ

ペロキシソーム増殖器活性化受容体アルファ (PPAR-α) アゴニストは,グルココルチコイドと併用すると,初期の原始細胞を刺激することによって赤血球の産生を促進します. この組み合わせは,エリトロポエチン耐性貧血の治療に有望であることが示されています.

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