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関連する概念動画

Membrane Fluidity01:23

Membrane Fluidity

179.7K
Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
179.7K
Membrane Fluidity01:26

Membrane Fluidity

18.1K
Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is...
18.1K
Factors Influencing Microbial Growth: Temperature01:27

Factors Influencing Microbial Growth: Temperature

2.0K
Microorganisms display remarkable adaptations, enabling them to thrive in diverse ecological niches across a wide range of temperatures. Temperature profoundly influences microbial growth by affecting enzymatic activity, membrane fluidity, and other cellular processes.Each microorganism operates within a specific temperature range defined by three cardinal points: minimum, optimum, and maximum. Below the minimum temperature, membranes lose fluidity, halting transport processes. Above the...
2.0K
Effects of Temperature on Free Energy02:11

Effects of Temperature on Free Energy

29.8K
The spontaneity of a process depends upon the temperature of the system. Phase transitions, for example, will proceed spontaneously in one direction or the other depending upon the temperature of the substance in question. Likewise, some chemical reactions can also exhibit temperature-dependent spontaneities. To illustrate this concept, the equation relating free energy change to the enthalpy and entropy changes for the process is considered:
29.8K
Fluid Mosaic Model01:19

Fluid Mosaic Model

20.1K
Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane structure, proposed in 1935 by Hugh Davson and James Danielli, was the first model to be widely accepted in the scientific community. The model was based on the plasma membrane's "railroad track" appearance in early electron micrographs. Davson and Danielli theorized that the plasma membrane's structure resembled a sandwich...
20.1K
Effect of Temperature Change on Reaction Rate02:28

Effect of Temperature Change on Reaction Rate

5.7K
The Arrhenius equation,
5.7K

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関連する実験動画

Updated: Apr 12, 2026

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer
10:11

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Published on: April 19, 2021

4.3K

膜流動性に対する熱を上げること.

Weiwei Fan1, Ronald M Evans2

  • 1Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

Cell
|May 23, 2015
PubMed
まとめ

細胞は,膜の流動性を温度変化に適応させます. 熱によって誘発される酵素は,デサチュラゼを調節し,細胞膜の機能を維持することによって,脂質飽和を制御します.

科学分野:

  • 細胞生物学 細胞生物学
  • 分子生物学は分子生物学である.
  • バイオケミストリー バイオケミストリー

背景:

  • 細胞膜は,温度を超えて流動性を維持する必要があります.
  • 温度変動は,膜の完全性や機能に問題をもたらします.

研究 の 目的:

  • 熱に対する反応として細胞が膜流動性を調節するために使用する分子機構を解明する.
  • 熱ストレス下での膜ホメオスタシスの維持に関与する重要な調節体を特定する.

主な方法:

  • トランスクリプション分析
  • 酵素活性測定法による酵素活性測定法
  • リピドミカルプロファイリング

主要な成果:

  • 熱誘発性アシル-コア脱水素酵素を含む新しい調節回路が特定されました.
  • この酵素は,脂質脱飽和酵素を転写的に調節する.
  • アチル-CoA脱水素酵素は,脂質飽和度を調節することによって,細胞膜の流動性を制御する.

結論:

  • 細胞は,膜の流動性を温度に適応させるため,洗練された調節メカニズムを採用しています.

さらに関連する動画

Thermodynamics of Membrane Protein Folding Measured by Fluorescence Spectroscopy
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Thermodynamics of Membrane Protein Folding Measured by Fluorescence Spectroscopy

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Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography
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Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography

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関連する実験動画

Last Updated: Apr 12, 2026

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer
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Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

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Thermodynamics of Membrane Protein Folding Measured by Fluorescence Spectroscopy
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Thermodynamics of Membrane Protein Folding Measured by Fluorescence Spectroscopy

Published on: April 28, 2011

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Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography
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Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography

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  • Acyl-CoA脱酸化酵素は,脂質不飽和酵素の活性を制御することによって,熱への適応に重要な役割を果たします.