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Updated: Apr 11, 2026

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
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細胞の粘着. 細胞の粘着. 細胞の粘着. 機械的なストレスは,E-カデリン依存のYap1とβ-カテニンの活性化を誘導し,細胞循環への侵入を促します

Blair W Benham-Pyle1, Beth L Pruitt2, W James Nelson3

  • 1Program in Cancer Biology, Stanford University, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|May 30, 2015
PubMed
まとめ

機械的なストレスは,Yap1とβ-catenin経路を通じた細胞増殖を誘発する. E-カデリンは,上皮細胞のこれらの機械信号応答に不可欠であり,組織発達を調節します.

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