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Updated: Apr 11, 2026

Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins
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ピクロミシンポリケチド合成酵素からの脱水酵素ドメインの機能的特徴化

Yang Li1, Greg J Dodge2, William D Fiers1

  • 1†Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, United States.

Journal of the American Chemical Society
|June 2, 2015
PubMed
まとめ

この研究は,ポリケチド合成酵素 (PKS) から PikDH2脱水酵素 (DH) ドメインを特徴付け,不飽和化合物を生成するメカニズムを明らかにします. この研究は,代謝工学による新しい天然製品の発見を可能にします.

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