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Updated: Apr 11, 2026

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
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Published on: May 4, 2018

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ペプチドグリカン修正は,先天性免疫受容体 Nod2 の安定性と機能を調節する

James E Melnyk1, Vishnu Mohanan1, Amy K Schaefer1

  • 1†Department of Chemistry and Biochemistry, and §Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, United States.

Journal of the American Chemical Society
|June 3, 2015
PubMed
まとめ

ペプチドグリカン・リガンドを改変することで,Nod2受容体を安定させ,先天的な免疫反応を微調整します. 研究者らは,リガンド構造を調整する新しい合成を開発し,治療の可能性のためのNod2活性化の調節を可能にしました.

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