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Updated: Apr 11, 2026

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

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ライシン結合状態に閉じ込められたシトクロームcのコンパクトな構造:ループの再折り畳みと適合スイッチの機能的影響

Jeanine F Amacher1, Fangfang Zhong2, George P Lisi2

  • 1†Department of Biochemistry, Geisel School of Medicine, Hanover, New Hampshire 03755, United States.

Journal of the American Chemical Society
|June 4, 2015
PubMed
まとめ

シトクロームc (cytc) のアルカリ的形態は構造変化を起こし,LysがMet80.0を代用する. この構造的シフトは,その過酸化酵素の活性性を高め,アポトーシスの役割をサポートします.

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Protein Folding01:25

Protein Folding

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Export of Misfolded Proteins out of the ER

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Covalently Linked Protein Regulators

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